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Ravgen was founded in 2000 by Dr. Ravinder Dhallan, M.D./Ph.D., M.B.A., a graduate of The Johns Hopkins University School of Medicine, with the goal of changing the paradigm of prenatal diagnostics. The current paradigm is almost exclusively focused on Downs syndrome testing, however, there are many other genetic conditions and reasons to offer patients prenatal diagnosis. For example, there are hundreds of single gene disorders, such as cystic fibrosis and sickle cell anemia among others, which can be better treated with early diagnosis. Dr. Dhallan and his team have spent the last decade working with fetal DNA present in the mother's blood developing safe, noninvasive tests to expand upon the current options available to patients. |
| Our work has been published in widely recognized and internationally accepted, peer reviewed journals. Click on the links below to see about our publications on noninvasive fetal DNA testing: |
| New England Journal of Medicine | The Lancet | Journal of the American Medical Association |
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| A non-invasive test for prenatal diagnosis based on fetal DNA present in maternal blood: a preliminary study | Methods to increase the percentage of free fetal DNA recovered from the maternal circulation |
| Prenatal DNA Paternity Test Ravgen is focused on developing non-invasive prenatal diagnostic tests based on fetal DNA present in maternal blood. The publicity surrounding our publications generated a large number of phone calls from patients requesting various non-invasive prenatal tests even on a research basis. These phone calls opened our eyes to a significant unmet clinical need which compelled us to develop a non-invasive Prenatal DNA Paternity Test. |
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| Ravgen's focus is on noninvasive prenatal diagnostics from fetal DNA in mother's blood. This has led to the development of a noninvasive prenatal paternity test. In 2008, our Prenatal DNA Paternity technology was used in the prosecution of the Michael Rosenboro murder trial of Lancaster County, Pennsylvania. Click the link to the right to see a description of how our Prenatal DNA Paternity Test was used in this case as told by true-crime novelist, M. William Phelps, in his 2011 book on this case: |
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Visit our news page for links to the book as well as other articles highlighting Ravgen's technology. Click on the links below to see a few of the articles covering Ravgen publications: