Ravgen was founded in 2000 by Dr. Ravinder Dhallan, M.D./Ph.D., M.B.A., a graduate of The Johns Hopkins University School of Medicine, with the goal of changing the paradigm of prenatal diagnostics.  The current paradigm is almost exclusively focused on Downs syndrome testing, however, there are many other genetic conditions and reasons to offer patients prenatal diagnosis.  For example, there are hundreds of single gene disorders, such as cystic fibrosis and sickle cell anemia among others, which can be better treated with early diagnosis.  Dr. Dhallan and his team have spent the last decade working with fetal DNA present in the mother's blood developing safe, noninvasive tests to expand upon the current options available to patients.

Methods to Increase the Percentage of Free Fetal DNA Recovered from the Maternal Circulation

Ravgen's focus is on noninvasive prenatal diagnostics from fetal DNA in mother's blood. This has led to the development of a noninvasive prenatal paternity test.  In 2008, our Prenatal DNA Paternity technology was used in the prosecution of the Michael Rosenboro murder trial of Lancaster County, Pennsylvania. Click the link to the right to see a description of how our Prenatal DNA Paternity Test was used in this case as told by true-crime novelist, M. William Phelps, in his 2011 book on this case:     

"Love Her To Death"